HPLC Column, NP Amino, 3um, 4.6mm ID x 100mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent NP Amino™ is a normal-phase and HILIC stationary phase designed for the retention and separation of highly polar compounds. Manufactured using a three-carbon propyl ligand with a terminal amino functional group bonded to high-purity silica, this stationary phase provides selectivity that is particularly useful for carbohydrates, organic acids, and other polar analytes. As a USP L8 equivalent phase, it is widely used as an alternative in established USP methods and for new method development involving Normal Phase and HILIC chromatography.

68340-10P is an HPLC column packed with 3 µm NP Amino™ particles featuring a 100 Å pore size in a 4.6 mm ID x 100 mm format. The 100 mm length provides an excellent balance between chromatographic resolution and analysis speed, while the 3 µm particles provide greater efficiency and sharper peaks than comparable 5 µm columns. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, temperature, and system configuration.

This column is particularly useful for the analysis of sugars, carbohydrates, compounds containing carboxylic acid groups, and other polar molecules. Suitable for both Normal Phase and HILIC chromatography, the amino functionality provides retention characteristics that make it valuable for analytes that are poorly retained on conventional reversed-phase columns. As an unmodified silica bonded amino phase, it is also suitable for HILIC applications.

Key Benefits

  • NP Amino™ stationary phase

  • USP L8 equivalent chemistry

  • Amino bonded phase

  • High-purity silica support

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Enhanced retention of polar compounds

  • 3 µm particle size

  • Greater efficiency than 5 µm columns

  • Balanced speed and resolution

Typical Applications

  • USP L8 methods

  • Sugar analysis

  • Carbohydrate analysis

  • Organic acid analysis

  • Polar compound analysis

  • HILIC methods

  • Normal Phase chromatography

  • Food and beverage analysis

  • Pharmaceutical analysis

  • Method development

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: NP Amino™

  • USP Classification: L8

  • Chromatography Modes: Normal Phase and HILIC

  • Bonded Phase: Amino

  • Endcapping: Not End Capped

  • Particle Size: 3 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.6 mm ID x 100 mm

  • Length: 100 mm

  • Typical Flow Rate: 0.8–1.5 mL/min

  • Brand: Cogent

Important Notes

  • Designed for highly polar compounds

  • Commonly used for sugars and compounds containing carboxylic acid groups

  • Suitable for both Normal Phase and HILIC chromatography

  • As an unmodified silica bonded amino phase, this column is suitable for HILIC applications

  • The 100 mm length provides greater resolution than 50 mm columns while maintaining practical run times

  • 3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns

  • Generates higher backpressure than larger particle columns

  • Packed and shipped in Normal Phase solvents

  • Provides an excellent alternative for USP L8 methods


 

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